Research

Nanostructures & Characterization | Cumputational Modeling | Micro/Nano Biosensors | Bioengineering |

        In this area, we use commercial multiphysics modeling software packages (e.g., COMSOL, ALGOR) to perform simulations of the nanoscale problems in a multidisciplinary manner by considering, if necessary, the mechanical, structural, electromagnetic, heat transfer, mass diffusion and balance, and fluidic phenomena simultaneously.

Modeling of Nano-electrodes

Diffusion controlled redox cycling behavior at nanoscale interdigitated electrodes (IDEs) was simulated using Comsol Multiphysics. Cyclic voltammograms were obtained for IDEs with various sizes and spacing, and current collection efficiency and cycling number were calculated. We found that as the size of the IDEs decreased, the shape of the voltammogram changed from a peak-shaped curve to a sigmoidal curve; as the spacing between generators and collectors decreased, the sigmoidal steady-state current density increased. This study provided new insight into achieving efficient and steady-state response with nanoscale IDEs for the development of highly sensitive and rapid-responding sensors and biosensors.

Modeling of Cranial Sutures

Two dimensional finite element analysis (FEA) was performed on various suture wavy patterns to identify the stress conditions at the bone/suture interface in order to understand the biomechanical process of formation of cranial sutures with various degrees of complexity.